We study ion translocating mechanisms (channels, exchangers and pumps) in health and disease. Our main focus is the KATP channel, which is responsible for metabolo-electrical coupling (the coupling of intracellular energy metabolism to membrane excitability and secretion). Using genetically engineered mouse models, we investigate the roles of roles for this channel in cardioprotection and the regulation of blood flow. We also pursue molecular studies to investigate regulation of channel function and trafficking by associated proteins.
NIH Funding Opportunities
- Notice of Pre-Application Webinar for PAR-16-361 "Research Initiative for Scientific Enhancement (RISE) Program (R25)"
- Grant Application Instruction Correction for Training Grants with Human Subjects Involvement
- Medications Development for the Treatment of Alcohol Use Disorder - CT optional (U01)
- Health Services and Economic Research on the Prevention and Treatment of Drug, Alcohol, and Tobacco Abuse (R01, Clinical Trial Optional)
- Notice of NIDDK's Withdrawal from Participation in PAR-18-530 "Academic-Industrial Partnerships for Translation of Technologies for Diagnosis and Treatment (R01 - Clinical Trial Optional)"